Influence of culturing on the survival of major histocompatibility complex- compatible and -incompatible thyroid grafts in rats
نویسندگان
چکیده
Culturing Fischer thyroid fragments promotes their survival in major histocompatibility complex (MHC) -incompatible ACI rats but not in MHC- compatible Lewis animals.
منابع مشابه
Evidence for major histocompatibility complex restriction in transplantation immunity.
Studies on the survival of histocompatibility-Y antigen (H-Y)-incompatible and skin-specific antigen (Skn)-incompatible skin grafts in mice, as well as those concerned with the survival of cultured parathyroid allografts in rats, indicate that grafts provoke a strong immune response only if they include donor macrophages (or Langerhans cells) or if major histocompatibility complex-compatible ma...
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The attributes of the test grafts with which putatively tolerant rats are challenged influence their immune response. Lewis (Lew) rats inoculated at birth with Lew/BN F1 hybrid bone marrow cells accept large skin allografts more readily than small allografts, and F1 hybrid skin grafts survive better than BN transplants. The results indicate that the survivals of these major histocompatibility c...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 157 شماره
صفحات -
تاریخ انتشار 1983